About The Company & The Job

PMC Group is a global chemicals and pharmaceutical conglomerate headquartered in Mt. Laurel, New Jersey, with research and manufacturing facilities spanning across the U.S., Europe, and Asia. Its annual revenue is close to $1 billion and the company is 100% owned by the Chakrabarti Family. Several of PMC Group’s subsidiaries were previously subsidiaries of leading global corporations, including BASF, AkzoNobel, Dow, ICI, Arkema, PPG Industries, ExxonMobil, and France’s SNPE. PMC Group’s pharmaceutical division – which spans locations in New Jersey; Paris, France; and Hyderabad, India -- is comprised of research, product/process development, regulatory approvals, pilot scale and full plant-scale production of drug intermediates and active pharma ingredients (APIs) to serve global needs in Oncology, Cardiovascular, Infectious, Gastro-Intestinal, Neurology and rare diseases.

Within PMC group, CCM Biosciences is an evergreen fund with a focus on start-up stage biotech companies. CCM Biosciences has assembled a portfolio of disruptive preclinical/clinical assets many of which are first-in-class or best-in-class drug programs.

The pipeline spans precision oncology, autoimmune disorders and chronic, age-related diseases and modalities and includes small molecules, biologics and nano-medicines. CCM Biosciences is currently seeking a highly skilled manager to lead several drug discovery and development programs that constitute an important part of PMC Group’s pharmaceutical growth initiatives.

Essential Job Functions & Responsibilities

• Manage several preclinical drug development programs.
• Oversee the design and planning, interpretation and communication of the preclinical drug development from the drug discovery phase to the IND filing, including CMC, Efficacy, ADME/Tox, PK/PD studies.
• Supervise any needed outsourcing of experiments through contract research organizations (CROs), describing the needed experiments to the CROs, following the progress and analyzing the results.
• Analyze and report results to the corporate management, identify bottlenecks and improve throughput.
• Analyze the scientific and patent literature pertaining to applications of interest to the group in order to assess the scope for proprietary improvements.
• Collaborate closely with the key stake-holders of the project.
• Develop a deep understanding of the program biology/pharmacology and be an active partner on project teams, providing scientific leadership and strategic guidance.
• Represent the program at project review and portfolio governance meetings. Draft scientific papers and patent applications.
• All other duties as assigned.

Knowledge, Skills & Abilities

• Broad insights into various DMPK relevant areas such as physicochemical properties, drug metabolizing enzymes and transporter kinetics, mechanistic biotransformation, in silico predictions, and qualitative and quantitative bioanalytical techniques.
• Display sound judgement in identifying and translating key findings from large datasets into clear & tangible project relevant actions. Pro-actively work towards early anticipation and mitigation of possible program challenges.
• Very good communicating skills.
• Organized, rigorous and autonomous.
• A track record or meeting or exceeding deadlines.
• Resulting focused.
• Enthusiasm and team spirit, good management skills.
• Ability to work in an interdisciplinary and international environment.

Working Conditions

• The location of this role is Mount Laurel, NJ (USA)
• The job holder will work in an office environment and must be willing to multi-task between various managers and responsibilities to accomplish the day’s requests.
• Ability to get along with others and not work in isolation is required.
• Must be able to travel occasionally to remote locations or customers including international.
• Ability to function effectively in a global business environment with production, technical CROs, regulatory agencies and management.

Education, Training, and Experience Required

• PhD in the field of pharmacokinetics, drug metabolism, or related discipline with 3+ years relevant pharmaceutical industry experience within preclinical department; or MS in pharmaceutical sciences, biomedical sciences or medicinal chemistry with 5+ years of relevant industry experience within preclinical department.
• Strong understanding and hands-on experience in characterizing the pre-clinical ADME profile of small molecule drugs. Complementary experiences in other modalities (peptides, oligonucleotides, PROTAC) is a plus.

PLEASE INCLUDE SALARY REQUIREMENTS WHEN APPLYING

Job Type: Full-time

Benefits:

• 401(k)
• Dental insurance
• Employee assistance program
• Health insurance
• Life insurance
• Paid time off
• Vision insurance

Schedule:

• 8 hour shift

Work Location: In person

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