COMPANY:

At BioCryst, we are passionate about advancing novel therapeutics for patients with rare and serious diseases. Our structure-guided drug design process leads us to the discovery and development of novel small-molecule drugs. We integrate traditional biology and medicinal chemistry along with a wide array of advanced technologies to understand the three-dimensional structures of active sites of target enzymes. Our scientists then design molecular structures to create bespoke drugs for patients. We focus on therapeutic areas with either no available treatments or large unmet patient needs. BioCryst’s US headquarters are located in Durham, North Carolina, our European headquarters in Dublin, Ireland and our Discovery Center of Excellence in Birmingham, Alabama. We are proud of our culture of engagement and accountability that rewards people for innovative thinking and achievement of key objectives. For more information, please visit the Company’s website at www.biocryst.com.

JOB SUMMARY:

This Research Chemist role provides a career track for a chemist that performs synthesis of a new drug molecule using their acquired knowledge. The employee's responsibilities range from performing independently standardized experiments or new experiments. The candidate must have the ability to identify the new drug molecule synthesized using various analytical tools.

ESSENTIAL DUTIES & RESPONSIBILITIES:

• Designing of most appropriate, economical and feasible synthetic routes for given target molecules
• Setup reactions and synthesize compounds for the target molecules, knowledge of purification of compounds using various purification techniques. Ability to characterize purified compounds by interpreting spectral data
• Ensure all Lab safety rules are followed and day to day work is conducted in a safe manner
• Plan independently day to day work
• Submission of the pure characterized molecules to the database
• Develop a synthetic strategy for target molecules
• Seek advice and input, if needed, from the supervisor or other resources on complex issues.
• Participate in weekly departmental drug discovery team meeting
• Ability to provide solutions to existing problems and be a participant in the drug discovery team
• May provide technical guidance to laboratory or field personnel
• Plan and Independently set up experiments, purify and characterize the synthesized compounds
• Design schemes for the synthesis of the target molecules
• Responsible for day to day operation of a discovery project
• Maintain proper documentation of the experiments conducted
• Ensure equipment assigned are maintained and fully functional for the group without any breakdown
• All other duties as assigned

EXPERIENCE & QUALIFICATIONS:

• Ph.D. in organic or medicinal chemistry with 0-2 years experience in the same field of science or an equivalent combination of education and experience
• Experience preferably gained in the biotech industry
• Ability to provide solutions to existing problems and be a participant in the drug discovery team
• Ability to prepare technical reports on the work performed
• Good documentation of the experiments conducted daily
• Excellent written and verbal communication skills

The statements in this position description are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. The manager may assign additional responsibilities and assignments from time to time.

BioCryst is an equal opportunity employer and is committed to providing equal employment opportunities without regard to age, race, religion, sex, sexual orientation, gender identity, national origin, Veterans status, disability and/or other protected class characteristics. Additionally, BioCryst is committed to achieving its business objectives in compliance with all federal, state and local law.

Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)